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Is RAGE still a therapeutic target for Alzheimer's disease?
The receptor for advanced glycation end products (RAGE) is a multiligand receptor involved in inflammatory disorders, tumor outgrowth, diabetic complications and Alzheimer's disease (AD). RAGE transports circulating amyloid-β toxins across the blood–brain barrier (BBB) into the brain. RAGE–amyl...
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| Publicado no: | Future Med Chem |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4973574/ https://ncbi.nlm.nih.gov/pubmed/22571615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.12.51 |
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