The Complexity of Sporadic Alzheimer's Disease Pathogenesis: The Role of RAGE as Therapeutic Target to Promote Neuroprotection by Inhibiting Neurovascular Dysfunction

Alzheimer's disease (AD) is the most common cause of dementia. Amyloid plaques and neurofibrillary tangles are prominent pathological features of AD. Aging and age-dependent oxidative stress are the major nongenetic risk factors for AD. The beta-amyloid peptide (Aβ), the major component of plaq...

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Detaylı Bibliyografya
Asıl Yazarlar: Perrone, Lorena, Sbai, Oualid, Nawroth, Peter P., Bierhaus, Angelika
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Hindawi Publishing Corporation 2012
Konular:
Review Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310161/
https://ncbi.nlm.nih.gov/pubmed/22482078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/734956
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