The helminth T2 RNase ω1 promotes metabolic homeostasis in an IL-33– and group 2 innate lymphoid cell–dependent mechanism

Induction of a type 2 cellular response in the white adipose tissue leads to weight loss and improves glucose homeostasis in obese animals. Injection of obese mice with recombinant helminth-derived Schistosoma mansoni egg-derived ω1 (ω1), a potent inducer of type 2 activation, improves metabolic sta...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Hams, Emily, Bermingham, Rachel, Wurlod, Felicity A., Hogan, Andrew E., O’Shea, Donal, Preston, Roger J., Rodewald, Hans-Reimer, McKenzie, Andrew N. J., Fallon, Padraic G.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2016
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973506/
https://ncbi.nlm.nih.gov/pubmed/26490658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-277822
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