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Structure of the human DNA-repair protein RAD52 containing surface mutations

The Rad52 protein is a eukaryotic single-strand DNA-annealing protein that is involved in the homologous recombinational repair of DNA double-strand breaks. The isolated N-terminal half of the human RAD52 protein (RAD52(1–212)) forms an undecameric ring structure with a surface that is mostly positi...

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Veröffentlicht in:Acta Crystallogr F Struct Biol Commun
Hauptverfasser: Saotome, Mika, Saito, Kengo, Onodera, Keiichi, Kurumizaka, Hitoshi, Kagawa, Wataru
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973300/
https://ncbi.nlm.nih.gov/pubmed/27487923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X1601027X
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