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Structural Basis of Homology-Directed DNA Repair Mediated by RAD52
RAD52 mediates homologous recombination by annealing cDNA strands. However, the detailed mechanism of DNA annealing promoted by RAD52 has remained elusive. Here we report two crystal structures of human RAD52 single-stranded DNA (ssDNA) complexes that probably represent key reaction intermediates of...
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| 發表在: | iScience |
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| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Elsevier
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6137706/ https://ncbi.nlm.nih.gov/pubmed/30428330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2018.04.005 |
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