Loss of l(3)mbt leads to acquisition of the ping-pong cycle in Drosophila ovarian somatic cells

In Drosophila germ cells, PIWI-interacting RNAs (piRNAs) are amplified through a PIWI slicer-dependent feed-forward loop termed the ping-pong cycle, yielding secondary piRNAs. However, the detailed mechanism remains poorly understood, largely because an ex vivo model system amenable to biochemical a...

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Detalles Bibliográficos
Publicado en:Genes Dev
Main Authors: Sumiyoshi, Tetsutaro, Sato, Kaoru, Yamamoto, Hitomi, Iwasaki, Yuka W., Siomi, Haruhiko, Siomi, Mikiko C.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2016
Assuntos:
Research Communication
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973291/
https://ncbi.nlm.nih.gov/pubmed/27474440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.283929.116
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