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Suppression of amyloid fibrils using the GroEL apical domain

In E. coli cells, rescue of non-native proteins and promotion of native state structure is assisted by the chaperonin GroEL. An important key to this activity lies in the structure of the apical domain of GroEL (GroEL-AD) (residue 191–376), which recognizes and binds non-native protein molecules thr...

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Publicat a:Sci Rep
Autors principals: Ojha, Bimlesh, Fukui, Naoya, Hongo, Kunihiro, Mizobata, Tomohiro, Kawata, Yasushi
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973282/
https://ncbi.nlm.nih.gov/pubmed/27488469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31041
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