TLR9 re-expression in cancer cells extends the S-phase and stabilizes p16(INK4a) protein expression

Toll-like receptor 9 (TLR9) recognizes bacterial, viral or cell damage-associated DNA, which initiates innate immune responses. We have previously shown that TLR9 expression is downregulated in several viral induced cancers including HPV16-induced cervical neoplasia. Findings supported that downregu...

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Detalhes bibliográficos
Publicado no:Oncogenesis
Main Authors: Parroche, P, Roblot, G, Le Calvez-Kelm, F, Tout, I, Marotel, M, Malfroy, M, Durand, G, McKay, J, Ainouze, M, Carreira, C, Allatif, O, Traverse-Glehen, A, Mendiola, M, Pozo-Kreilinger, J J, Caux, C, Tommasino, M, Goutagny, N, Hasan, U A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972902/
https://ncbi.nlm.nih.gov/pubmed/27454079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2016.49
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