The Human papillomavirus type 16 E7 oncoprotein induces a transcriptional repressor complex on the Toll-like receptor 9 promoter

Human papillomavirus type 16 (HPV16) and other oncogenic viruses have been reported to deregulate immunity by suppressing the function of the double-stranded DNA innate sensor TLR9. However, the mechanisms leading to these events remain to be elucidated. We show that infection of human epithelial ce...

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Hauptverfasser: Hasan, Uzma A., Zannetti, Claudia, Parroche, Peggy, Goutagny, Nadège, Malfroy, Marine, Roblot, Guillaume, Carreira, Christine, Hussain, Ishraq, Müller, Martin, Taylor-Papadimitriou, Joyce, Picard, Didier, Sylla, Bakary S., Trinchieri, Giorgio, Medzhitov, Ruslan, Tommasino, Massimo
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698525/
https://ncbi.nlm.nih.gov/pubmed/23752229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20122394
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