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GATA-3 REGULATES THE SELF-RENEWAL OF LONG-TERM HEMATOPOIETIC STEM CELLS

Gata3 is expressed and required for differentiation and function throughout the T lymphocyte lineage. Despite evidence it may also be expressed in multipotent hematopoietic stem cells (HSC), any role in these cells has remained unclear. Here we show GATA3 was cytoplasmic in quiescent long-term stem...

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Detalhes bibliográficos
Publicado no:Nat Immunol
Main Authors: Frelin, Catherine, Herrington, Robert, Janmohamed, Salima, Barbara, Mary, Tran, Gary, Paige, Christopher J., Benveniste, Patricia, Zuñiga-Pflücker, Juan-Carlos, Souabni, Abdallah, Busslinger, Meinrad, Iscove, Norman N
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972578/
https://ncbi.nlm.nih.gov/pubmed/23974957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2692
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