GATA-3 REGULATES THE SELF-RENEWAL OF LONG-TERM HEMATOPOIETIC STEM CELLS

Gata3 is expressed and required for differentiation and function throughout the T lymphocyte lineage. Despite evidence it may also be expressed in multipotent hematopoietic stem cells (HSC), any role in these cells has remained unclear. Here we show GATA3 was cytoplasmic in quiescent long-term stem...

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Pubblicato in:Nat Immunol
Autori principali: Frelin, Catherine, Herrington, Robert, Janmohamed, Salima, Barbara, Mary, Tran, Gary, Paige, Christopher J., Benveniste, Patricia, Zuñiga-Pflücker, Juan-Carlos, Souabni, Abdallah, Busslinger, Meinrad, Iscove, Norman N
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972578/
https://ncbi.nlm.nih.gov/pubmed/23974957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2692
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