Regulation of GATA-3 expression during CD4 lineage differentiation

GATA-3 is necessary for the development of MHC II-restricted CD4 T cells, and its expression is increased during positive selection of these cells. TcR signals drive this upregulation, but the signaling pathways that control this process are not well understood. Using genetic and pharmacological app...

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Bibliografiske detaljer
Main Authors: Gimferrer, Idoia, Hu, Taishan, Simmons, Amie, Wang, Chi, Souabni, Abdallah, Busslinger, Meinrad, Bender, Timothy P., Hernandez-Hoyos, Gabriela, Alberola-Ila, José
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074202/
https://ncbi.nlm.nih.gov/pubmed/21357543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003505
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