Highly Stable, Amide-Bridged Autoinducing Peptide Analogues that Strongly Inhibit the AgrC Quorum Sensing Receptor in Staphylococcus aureus

Blocking quorum sensing (QS) pathways has attracted considerable interest as an approach to suppress virulence in bacterial pathogens. Toward this goal, we recently developed analogues of a native autoinducing peptide (AIP-III) signal that can inhibit AgrC-type QS receptors and attenuate virulence p...

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Vydáno v:Angew Chem Int Ed Engl
Hlavní autoři: Tal-Gan, Yftah, Ivancic, Monika, Cornilescu, Gabriel, Yang, Tian, Blackwell, Helen E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972187/
https://ncbi.nlm.nih.gov/pubmed/27276693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201602974
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