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Highly Stable, Amide-Bridged Autoinducing Peptide Analogues that Strongly Inhibit the AgrC Quorum Sensing Receptor in Staphylococcus aureus

Blocking quorum sensing (QS) pathways has attracted considerable interest as an approach to suppress virulence in bacterial pathogens. Toward this goal, we recently developed analogues of a native autoinducing peptide (AIP-III) signal that can inhibit AgrC-type QS receptors and attenuate virulence p...

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Bibliografische gegevens
Gepubliceerd in:Angew Chem Int Ed Engl
Hoofdauteurs: Tal-Gan, Yftah, Ivancic, Monika, Cornilescu, Gabriel, Yang, Tian, Blackwell, Helen E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972187/
https://ncbi.nlm.nih.gov/pubmed/27276693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201602974
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