Injection site reactions after subcutaneous oligonucleotide therapy

Oligonucleotides (ONs) are short fragments of nucleic acids, currently being investigated as therapeutic agents. When administered subcutaneously (sc), ONs cause a specific local reaction originating around the injection site, such as erythema, itching, discomfort and pain, including more severe man...

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Библиографические подробности
Опубликовано в: :Br J Clin Pharmacol
Главные авторы: van Meer, Leonie, Moerland, Matthijs, Gallagher, Jolie, van Doorn, Martijn B. A., Prens, Errol P., Cohen, Adam F., Rissmann, Robert, Burggraaf, Jacobus
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2016
Предметы:
Reviews
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972150/
https://ncbi.nlm.nih.gov/pubmed/27061947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12961
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