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When Myc's asleep, embryonic stem cells are dormant

Myc is one of the original reprogramming factors used to produce induced pluripotent stem cells. However, it is not necessary, instead its main role is to increase the efficiency of the reprogramming. The article by Scognamiglio et al (2016) helps clarify how. The authors show that Myc depletion lea...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Nakagawa, Masato, Karagiannis, Peter, Yamanaka, Shinya
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972139/
https://ncbi.nlm.nih.gov/pubmed/26968984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201694095
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