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Myc-regulated microRNAs attenuate embryonic stem cell differentiation

Myc proteins are known to have an important function in stem cell maintenance. As Myc has been shown earlier to regulate microRNAs (miRNAs) involved in proliferation, we sought to determine whether c-Myc also affects embryonic stem (ES) cell maintenance and differentiation through miRNAs. Using a qu...

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Hlavní autoři: Lin, Chin-Hsing, Jackson, Aimee L, Guo, Jie, Linsley, Peter S, Eisenman, Robert N
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744176/
https://ncbi.nlm.nih.gov/pubmed/19745813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.254
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