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Myc-regulated microRNAs attenuate embryonic stem cell differentiation

Myc proteins are known to have an important function in stem cell maintenance. As Myc has been shown earlier to regulate microRNAs (miRNAs) involved in proliferation, we sought to determine whether c-Myc also affects embryonic stem (ES) cell maintenance and differentiation through miRNAs. Using a qu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lin, Chin-Hsing, Jackson, Aimee L, Guo, Jie, Linsley, Peter S, Eisenman, Robert N
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744176/
https://ncbi.nlm.nih.gov/pubmed/19745813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.254
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