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InsP(3)R, the calcium whisperer: Maintaining mitochondrial function in cancer

Mitochondrial metabolism is essential to fulfill the large demand for macromolecule biosynthesis in cancer. We recently identified low-level InsP(3)R-mediated Ca(2+) transfer to mitochondria as an unexpected requirement for mitochondrial function. Here we reveal that its absence specifically targets...

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Bibliografske podrobnosti
izdano v:Mol Cell Oncol
Main Authors: Lovy, Alenka, Foskett, J. Kevin, Cárdenas, César
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972124/
https://ncbi.nlm.nih.gov/pubmed/27652328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1185563
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