Does PTEN gene mutation play any role in Li-Fraumeni syndrome

Background: Li-Fraumeni syndrome (LFS) is one of the most serious hereditary cancer syndromes with a high risk of malignancy in childhood. This syndrome is an autosomal dominant cancer predisposing syndrome due to a germline mutation in the TP53 tumor suppressor gene. Methods: In this study, a repre...

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Publicat a:Med J Islam Repub Iran
Autors principals: Akouchekian, Mansoureh, Hemati, Simin, Jafari, Davood, Jalilian, Nazanin, Dehghan Manshadi, Masoumeh
Format: Artigo
Idioma:Inglês
Publicat: Iran University of Medical Sciences 2016
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972054/
https://ncbi.nlm.nih.gov/pubmed/27493922
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