Insulin resistance after a 72-h fast is associated with impaired AS160 phosphorylation and accumulation of lipid and glycogen in human skeletal muscle

During fasting, human skeletal muscle depends on lipid oxidation for its energy substrate metabolism. This is associated with the development of insulin resistance and a subsequent reduction of insulin-stimulated glucose uptake. The underlying mechanisms controlling insulin action on skeletal muscle...

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Veröffentlicht in:Am J Physiol Endocrinol Metab
Hauptverfasser: Vendelbo, M. H., Clasen, B. F. F., Treebak, J. T., Møller, L., Krusenstjerna-Hafstrøm, T., Madsen, M., Nielsen, T. S., Stødkilde-Jørgensen, H., Pedersen, S. B., Jørgensen, J. O. L., Goodyear, L. J., Wojtaszewski, J. F. P., Møller, N., Jessen, N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2012
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971894/
https://ncbi.nlm.nih.gov/pubmed/22028408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00207.2011
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