Insulin stimulation regulates AS160 and TBC1D1 phosphorylation sites in human skeletal muscle

INTRODUCTION: Individuals with obesity and type 2 diabetes (T2D) are typically insulin resistant, exhibiting impaired skeletal muscle glucose uptake. Animal and cell culture experiments have shown that site-specific phosphorylation of the Rab-GTPase-activating proteins AS160 and TBC1D1 is critical f...

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Bibliografiske detaljer
Main Authors: Middelbeek, R J W, Chambers, M A, Tantiwong, P, Treebak, J T, An, D, Hirshman, M F, Musi, N, Goodyear, L J
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697402/
https://ncbi.nlm.nih.gov/pubmed/23752133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nutd.2013.13
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