TBR1 regulates autism risk genes in the developing neocortex

Exome sequencing studies have identified multiple genes harboring de novo loss-of-function (LoF) variants in individuals with autism spectrum disorders (ASD), including TBR1, a master regulator of cortical development. We performed ChIP-seq for TBR1 during mouse cortical neurogenesis and show that T...

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Dades bibliogràfiques
Publicat a:Genome Res
Autors principals: Notwell, James H., Heavner, Whitney E., Darbandi, Siavash Fazel, Katzman, Sol, McKenna, William L., Ortiz-Londono, Christian F., Tastad, David, Eckler, Matthew J., Rubenstein, John L.R., McConnell, Susan K., Chen, Bin, Bejerano, Gill
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2016
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971772/
https://ncbi.nlm.nih.gov/pubmed/27325115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.203612.115
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