The use of digital PCR to improve the application of quantitative molecular diagnostic methods for tuberculosis

BACKGROUND: Real-time PCR (qPCR) based methods, such as the Xpert MTB/RIF, are increasingly being used to diagnose tuberculosis (TB). While qualitative methods are adequate for diagnosis, the therapeutic monitoring of TB patients requires quantitative methods currently performed using smear microsco...

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Detalhes bibliográficos
Publicado no:BMC Infect Dis
Main Authors: Devonshire, Alison S., O’Sullivan, Denise M., Honeyborne, Isobella, Jones, Gerwyn, Karczmarczyk, Maria, Pavšič, Jernej, Gutteridge, Alice, Milavec, Mojca, Mendoza, Pablo, Schimmel, Heinz, Van Heuverswyn, Fran, Gorton, Rebecca, Cirillo, Daniela Maria, Borroni, Emanuele, Harris, Kathryn, Barnard, Marinus, Heydenrych, Anthenette, Ndusilo, Norah, Wallis, Carole L., Pillay, Keshree, Barry, Thomas, Reddington, Kate, Richter, Elvira, Mozioğlu, Erkan, Akyürek, Sema, Yalçınkaya, Burhanettin, Akgoz, Muslum, Žel, Jana, Foy, Carole A., McHugh, Timothy D., Huggett, Jim F.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971652/
https://ncbi.nlm.nih.gov/pubmed/27487852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12879-016-1696-7
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