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The Thyroid Hormone Receptors Inhibit Hepatic Interleukin-6 Signaling During Endotoxemia

Decreased thyroidal hormone production is found during lipopolysaccharide (LPS)-induced endotoxic shock in animals as well as in critically ill patients. Here we studied the role of the thyroid hormone receptors (TRs) in activation of STAT3, NF-κB and ERK, which play a key role in the response to in...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Contreras-Jurado, Constanza, Alonso-Merino, Elvira, Saiz-Ladera, Cristina, Valiño, Arturo José, Regadera, Javier, Alemany, Susana, Aranda, Ana
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971531/
https://ncbi.nlm.nih.gov/pubmed/27484112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30990
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