Optogenetic and chemogenetic strategies for sustained inhibition of pain

Spatially targeted, genetically-specific strategies for sustained inhibition of nociceptors may help transform pain science and clinical management. Previous optogenetic strategies to inhibit pain have required constant illumination, and chemogenetic approaches in the periphery have not been shown t...

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Udgivet i:Sci Rep
Main Authors: Iyer, Shrivats M., Vesuna, Sam, Ramakrishnan, Charu, Huynh, Karen, Young, Stephanie, Berndt, Andre, Lee, Soo Yeun, Gorini, Christopher J., Deisseroth, Karl, Delp, Scott L.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971509/
https://ncbi.nlm.nih.gov/pubmed/27484850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30570
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