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Virally mediated optogenetic excitation and inhibition of pain in freely moving non-transgenic mice

Primary nociceptors are the first neurons involved in the complex processing system that regulates normal and pathological pain(1). Our ability to excite and inhibit these neurons has been limited by pharmacological and electrical stimulation constraints; non-invasive excitation and inhibition of th...

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Detalhes bibliográficos
Main Authors: Iyer, Shrivats Mohan, Montgomery, Kate L., Towne, Chris, Lee, Soo Yeun, Ramakrishnan, Charu, Deisseroth, Karl, Delp, Scott L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988230/
https://ncbi.nlm.nih.gov/pubmed/24531797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2834
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