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DNA damage, tumor mutational load and their impact on immune responses against cancer
Advances in immunotherapy have changed the therapeutic landscape in many malignancies. Immune checkpoint inhibitors have already received regulatory approval in melanomas, lung, renal and bladder carcinomas. A common feature of these neoplasms is the increased mutational load, related to a possible...
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| 出版年: | Ann Transl Med |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
AME Publishing Company
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4971372/ https://ncbi.nlm.nih.gov/pubmed/27563651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2016.07.11 |
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