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DNA damage, tumor mutational load and their impact on immune responses against cancer
Advances in immunotherapy have changed the therapeutic landscape in many malignancies. Immune checkpoint inhibitors have already received regulatory approval in melanomas, lung, renal and bladder carcinomas. A common feature of these neoplasms is the increased mutational load, related to a possible...
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| Publicado no: | Ann Transl Med |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
AME Publishing Company
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4971372/ https://ncbi.nlm.nih.gov/pubmed/27563651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2016.07.11 |
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