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Quantitative Assessment of the Effects of Water Proton Concentration and Water T(1) Changes on Amide Proton Transfer (APT) and Nuclear Overhauser Enhancement (NOE) MRI: The Origin of the APT Imaging Signal in Brain Tumor

PURPOSE: To quantify pure CEST-related APT and NOE signals in a rat glioma model and to investigate the mixed effects of water content and water T(1) on APT and NOE imaging signals. METHODS: Eleven U87 tumor-bearing rats were scanned at 4.7 T. A relatively accurate mathematical approach, based on ex...

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Detalhes bibliográficos
Publicado no:Magn Reson Med
Main Authors: Lee, Dong-Hoon, Heo, Hye-Young, Zhang, Kai, Zhang, Yi, Jiang, Shanshan, Zhao, Xuna, Zhou, Jinyuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970958/
https://ncbi.nlm.nih.gov/pubmed/26841096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.26131
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