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Quantitative Assessment of Amide Proton Transfer (APT) and Nuclear Overhauser Enhancement (NOE) Imaging with Extrapolated Semi-solid Magnetization Transfer Reference (EMR) Signals: Application to a Rat Glioma Model at 4.7 T

PURPOSE: To quantify APT and NOE contributions to in vivo chemical exchange saturation transfer MRI signals in tumors. THEORY AND METHODS: Two-pool (free water and semi-solid protons) and four-pool (free water, semi-solid, amide, and upfield NOE-related protons) tissue models combined with the super...

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發表在:Magn Reson Med
Main Authors: Heo, Hye-Young, Zhang, Yi, Lee, Dong-Hoon, Hong, Xiaohua, Zhou, Jinyuan
格式: Artigo
語言:Inglês
出版: 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4561043/
https://ncbi.nlm.nih.gov/pubmed/25753614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.25581
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