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Understanding intratumoral heterogeneity: lessons from the analysis of at-risk tissue and pre-malignant lesions in the colon

Advances in DNA sequencing have created new opportunities to better understand the biology of cancers. Attention is currently focused on precision medicine: does a cancer carry a mutation that is targetable with already available drugs? But, when multiple, targetable mutations arise during the adeno...

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Publicat a:Cancer Prev Res (Phila)
Autors principals: Sievers, Chelsie K., Leystra, Alyssa A., Clipson, Linda, Dove, William F., Halberg, Richard B.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970935/
https://ncbi.nlm.nih.gov/pubmed/27199343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-16-0096
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