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Effectiveness and mode of action of a combination therapy for heterotopic ossification with a retinoid agonist and an anti-inflammatory agent

Heterotopic ossification (HO) consists of ectopic cartilage and bone formation following severe trauma or invasive surgeries, and a genetic form of it characterizes patients with Fibrodysplasia Ossificans Progressiva (FOP). Recent mouse studies showed that HO was significantly inhibited by systemic...

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Detalhes bibliográficos
Publicado no:Bone
Main Authors: Sinha, Sayantani, Uchibe, Kenta, Usami, Yu, Pacifici, Maurizio, Iwamoto, Masahiro
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970925/
https://ncbi.nlm.nih.gov/pubmed/26891836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2016.02.008
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