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A novel multiple joint dislocation syndrome associated with a homozygous nonsense variant in the EXOC6B gene

We report two brothers from a consanguineous couple with spondyloepimetaphyseal dysplasia (SEMD), multiple joint dislocations at birth, severe joint laxity, scoliosis, gracile metacarpals and metatarsals, delayed bone age and poorly ossified carpal and tarsal bones, probably representing a yet uncha...

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Detalhes bibliográficos
Publicado no:Eur J Hum Genet
Main Authors: Girisha, Katta Mohan, Kortüm, Fanny, Shah, Hitesh, Alawi, Malik, Dalal, Ashwin, Bhavani, Gandham SriLakshmi, Kutsche, Kerstin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970677/
https://ncbi.nlm.nih.gov/pubmed/26669664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2015.261
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