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A novel multiple joint dislocation syndrome associated with a homozygous nonsense variant in the EXOC6B gene

We report two brothers from a consanguineous couple with spondyloepimetaphyseal dysplasia (SEMD), multiple joint dislocations at birth, severe joint laxity, scoliosis, gracile metacarpals and metatarsals, delayed bone age and poorly ossified carpal and tarsal bones, probably representing a yet uncha...

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Vydáno v:Eur J Hum Genet
Hlavní autoři: Girisha, Katta Mohan, Kortüm, Fanny, Shah, Hitesh, Alawi, Malik, Dalal, Ashwin, Bhavani, Gandham SriLakshmi, Kutsche, Kerstin
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970677/
https://ncbi.nlm.nih.gov/pubmed/26669664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2015.261
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