Social disinhibition is a heritable subphenotype of tics in Tourette syndrome

OBJECTIVE: To identify heritable symptom-based subtypes of Tourette syndrome (TS). METHODS: Forty-nine motor and phonic tics were examined in 3,494 individuals (1,191 TS probands and 2,303 first-degree relatives). Item-level exploratory factor and latent class analyses (LCA) were used to identify ti...

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發表在:Neurology
Main Authors: Hirschtritt, Matthew E., Darrow, Sabrina M., Illmann, Cornelia, Osiecki, Lisa, Grados, Marco, Sandor, Paul, Dion, Yves, King, Robert A., Pauls, David L., Budman, Cathy L., Cath, Danielle C., Greenberg, Erica, Lyon, Gholson J., Yu, Dongmei, McGrath, Lauren M., McMahon, William M., Lee, Paul C., Delucchi, Kevin L., Scharf, Jeremiah M., Mathews, Carol A.
格式: Artigo
語言:Inglês
出版: Lippincott Williams & Wilkins 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970665/
https://ncbi.nlm.nih.gov/pubmed/27371487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000002910
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