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Social disinhibition is a heritable subphenotype of tics in Tourette syndrome

OBJECTIVE: To identify heritable symptom-based subtypes of Tourette syndrome (TS). METHODS: Forty-nine motor and phonic tics were examined in 3,494 individuals (1,191 TS probands and 2,303 first-degree relatives). Item-level exploratory factor and latent class analyses (LCA) were used to identify ti...

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Detalhes bibliográficos
Publicado no:Neurology
Main Authors: Hirschtritt, Matthew E., Darrow, Sabrina M., Illmann, Cornelia, Osiecki, Lisa, Grados, Marco, Sandor, Paul, Dion, Yves, King, Robert A., Pauls, David L., Budman, Cathy L., Cath, Danielle C., Greenberg, Erica, Lyon, Gholson J., Yu, Dongmei, McGrath, Lauren M., McMahon, William M., Lee, Paul C., Delucchi, Kevin L., Scharf, Jeremiah M., Mathews, Carol A.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970665/
https://ncbi.nlm.nih.gov/pubmed/27371487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000002910
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