Studies on 16α-Hydroxylation of Steroid Molecules and Regioselective Binding Mode in Homology-Modeled Cytochrome P450-2C11

We investigated the 16α-hydroxylation of steroid molecules and regioselective binding mode in homology-modeled cytochrome P450-2C11 to correlate the biological study with the computational molecular modeling. It revealed that there was a positive relationship between the observed inhibitory potencie...

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Vydáno v:Int J Med Chem
Hlavní autoři: Ali, Hamed I., Yamada, Morio, Fujita, Yukihisa, Maeda, Mitsuko, Akaho, Eiichi
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2011
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970648/
https://ncbi.nlm.nih.gov/pubmed/27516905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/918168
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