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A Compact Structure of Cytochrome c Trapped in a Lysine-Ligated State: Loop Refolding and Functional Implications of a Conformational Switch

It has been suggested that the alkaline form of cytochrome c (cyt c) regulates function of this protein as an electron carrier in oxidative phosphorylation and as a peroxidase that reacts with cardiolipin (CL) during apoptosis. In this form, Met80, the native ligand to the heme iron, is replaced by...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Am Chem Soc
Main Authors: Amacher, Jeanine F., Zhong, Fangfang, Lisi, George P., Zhu, Michael Q., Alden, Stephanie L., Hoke, Kevin R., Madden, Dean R., Pletneva, Ekaterina V.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970523/
https://ncbi.nlm.nih.gov/pubmed/26038984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b01493
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