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Reduced Cationic Nanoparticle Cytotoxicity Based on Serum Masking of Surface Potential
Functionalization of nanoparticles with cationic moieties, such as polyethyleneimine (PEI), enhances binding to the cell membrane; however, it also disrupts the integrity of the cell’s plasma and vesicular membranes, leading to cell death. Primary fibroblasts were found to display high surface affin...
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| Publicado no: | J Biomed Nanotechnol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4970519/ https://ncbi.nlm.nih.gov/pubmed/27301181 |
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