Effects of dexmedetomidine and esmolol on systemic hemodynamics and exogenous lactate clearance in early experimental septic shock

BACKGROUND: Persistent hyperlactatemia during septic shock is multifactorial. Hypoperfusion-related anaerobic production and adrenergic-driven aerobic generation together with impaired lactate clearance have been implicated. An excessive adrenergic response could contribute to persistent hyperlactat...

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Detalhes bibliográficos
Publicado no:Crit Care
Main Authors: Hernández, Glenn, Tapia, Pablo, Alegría, Leyla, Soto, Dagoberto, Luengo, Cecilia, Gomez, Jussara, Jarufe, Nicolas, Achurra, Pablo, Rebolledo, Rolando, Bruhn, Alejandro, Castro, Ricardo, Kattan, Eduardo, Ospina-Tascón, Gustavo, Bakker, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4969982/
https://ncbi.nlm.nih.gov/pubmed/27480413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-016-1419-x
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