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Impairment of exogenous lactate clearance in experimental hyperdynamic septic shock is not related to total liver hypoperfusion

INTRODUCTION: Although the prognostic value of persistent hyperlactatemia in septic shock is unequivocal, its physiological determinants are controversial. Particularly, the role of impaired hepatic clearance has been underestimated and is only considered relevant in patients with liver ischemia or...

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Détails bibliographiques
Publié dans:Crit Care
Auteurs principaux: Tapia, Pablo, Soto, Dagoberto, Bruhn, Alejandro, Alegría, Leyla, Jarufe, Nicolás, Luengo, Cecilia, Kattan, Eduardo, Regueira, Tomás, Meissner, Arturo, Menchaca, Rodrigo, Vives, María Ignacia, Echeverría, Nicolas, Ospina-Tascón, Gustavo, Bakker, Jan, Hernández, Glenn
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432956/
https://ncbi.nlm.nih.gov/pubmed/25898244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-015-0928-3
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