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Impairment of exogenous lactate clearance in experimental hyperdynamic septic shock is not related to total liver hypoperfusion

INTRODUCTION: Although the prognostic value of persistent hyperlactatemia in septic shock is unequivocal, its physiological determinants are controversial. Particularly, the role of impaired hepatic clearance has been underestimated and is only considered relevant in patients with liver ischemia or...

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Pubblicato in:Crit Care
Autori principali: Tapia, Pablo, Soto, Dagoberto, Bruhn, Alejandro, Alegría, Leyla, Jarufe, Nicolás, Luengo, Cecilia, Kattan, Eduardo, Regueira, Tomás, Meissner, Arturo, Menchaca, Rodrigo, Vives, María Ignacia, Echeverría, Nicolas, Ospina-Tascón, Gustavo, Bakker, Jan, Hernández, Glenn
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432956/
https://ncbi.nlm.nih.gov/pubmed/25898244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-015-0928-3
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