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Impairment of exogenous lactate clearance in experimental hyperdynamic septic shock is not related to total liver hypoperfusion

INTRODUCTION: Although the prognostic value of persistent hyperlactatemia in septic shock is unequivocal, its physiological determinants are controversial. Particularly, the role of impaired hepatic clearance has been underestimated and is only considered relevant in patients with liver ischemia or...

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Bibliographic Details
Published in:Crit Care
Main Authors: Tapia, Pablo, Soto, Dagoberto, Bruhn, Alejandro, Alegría, Leyla, Jarufe, Nicolás, Luengo, Cecilia, Kattan, Eduardo, Regueira, Tomás, Meissner, Arturo, Menchaca, Rodrigo, Vives, María Ignacia, Echeverría, Nicolas, Ospina-Tascón, Gustavo, Bakker, Jan, Hernández, Glenn
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432956/
https://ncbi.nlm.nih.gov/pubmed/25898244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-015-0928-3
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