Specificity of antisense oligonucleotides in vivo.

Antisense oligonucleotides are widely used as inhibitors of gene expression in cultured cells and have been proposed as potential therapeutic agents, but it is not known to what extent they are specific for their intended target RNAs. Statistical considerations indicate that if oligonucleotides can...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Woolf, T M, Melton, D A, Jennings, C G
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49698/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1380154/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.16.7305
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