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Minimax and admissible adaptive two-stage designs in phase II clinical trials

BACKGROUND: Simon’s two-stage design is the most widely implemented among multi-stage designs in phase II clinical trials to assess the activity of a new treatment in a single-arm study. In this two-stage design, the sample size from the second stage is fixed regardless of the number of responses ob...

詳細記述

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書誌詳細
出版年:BMC Med Res Methodol
主要な著者: Shan, Guogen, Zhang, Hua, Jiang, Tao
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4969653/
https://ncbi.nlm.nih.gov/pubmed/27485595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-016-0194-3
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