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Distinct Differentiation Programs Triggered by IL-6 and LPS in Teleost IgM(+) B Cells in The Absence of Germinal Centers

Although originally identified as a B cell differentiation factor, it is now known that mammalian interleukin-6 (IL-6) only regulates B cells committed to plasma cells in response to T-dependent (TD) antigens within germinal centers (GCs). Even though adaptive immunity is present in teleost fish, th...

詳細記述

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書誌詳細
出版年:Sci Rep
主要な著者: Abós, Beatriz, Wang, Tiehui, Castro, Rosario, Granja, Aitor G., Leal, Esther, Havixbeck, Jeffrey, Luque, Alfonso, Barreda, Daniel R., Secombes, Chris J., Tafalla, Carolina
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4969607/
https://ncbi.nlm.nih.gov/pubmed/27481356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30004
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