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Quality control of nonstop membrane proteins at the ER membrane and in the cytosol

Since messenger RNAs without a stop codon (nonstop mRNAs) for organelle-targeted proteins and their translation products (nonstop proteins) generate clogged translocon channels as well as stalled ribosomes, cells have mechanisms to degrade nonstop mRNAs and nonstop proteins and to clear the transloc...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Arakawa, Shunsuke, Yunoki, Kaori, Izawa, Toshiaki, Tamura, Yasushi, Nishikawa, Shuh-ichi, Endo, Toshiya
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4969602/
https://ncbi.nlm.nih.gov/pubmed/27481473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30795
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