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Comparing the functions of equine and canine influenza H3N8 virus PA-X proteins: suppression of reporter gene expression and modulation of global host gene expression

The influenza PA-X protein is translated from the PA open reading frame from frameshifting and suppresses cellular gene expression due to its ribonuclease activity. We further defined the functional roles of PA-X by comparing PA-X proteins from two related viruses – equine influenza (EIV) and canine...

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Publicat a:Virology
Autors principals: Feng, Kurtis H., Sun, Miao, Iketani, Sho, Holmes, Edward C., Parrish, Colin R.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4969160/
https://ncbi.nlm.nih.gov/pubmed/27314620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2016.06.001
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