Subretinal mononuclear phagocytes induce cone segment loss via IL-1β

Photo-transduction in cone segments (CS) is crucial for high acuity daytime vision. For ill-defined reasons, CS degenerate in retinitis pigmentosa (RP) and in the transitional zone (TZ) of atrophic zones (AZ), which characterize geographic atrophy (GA). Our experiments confirm the loss of cone segme...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Eandi, Chiara M, Charles Messance, Hugo, Augustin, Sébastien, Dominguez, Elisa, Lavalette, Sophie, Forster, Valérie, Hu, Shulong Justin, Siquieros, Lourdes, Craft, Cheryl Mae, Sahel, José-Alain, Tadayoni, Ramin, Paques, Michel, Guillonneau, Xavier, Sennlaub, Florian
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Human Biology and Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4969036/
https://ncbi.nlm.nih.gov/pubmed/27438413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.16490
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