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Mutational analysis of primary and metastatic colorectal cancer samples underlying the resistance to cetuximab-based therapy
PURPOSE: Although several molecular markers predicting resistance to cetuximab- or panitumumab-based therapy of metastatic colorectal cancer were described, mutations in RAS proto-oncogenes remain the only predictors being used in daily clinical practice. However, 35%–45% of wild-type RAS patients s...
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| Pubblicato in: | Onco Targets Ther |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Dove Medical Press
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4968864/ https://ncbi.nlm.nih.gov/pubmed/27555788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S102891 |
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