MicroRNA expression profiling identifies miR-31-5p/3p as associated with time to progression in wild-type RAS metastatic colorectal cancer treated with cetuximab

The aim of our study was to investigate whether microRNAs (miRNAs) could serve as predictive biomarkers to anti-EGFR therapy (cetuximab, panitumumab) in patients with RAS wild-type (wt-RAS) metastatic colorectal cancer (mCRC). Historical cohort of 93 patients with mCRC (2006–2009) was included and f...

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Vydáno v:Oncotarget
Hlavní autoři: Mlcochova, Jitka, Faltejskova-Vychytilova, Petra, Ferracin, Manuela, Zagatti, Barbara, Radova, Lenka, Svoboda, Marek, Nemecek, Radim, John, Stanislav, Kiss, Igor, Vyzula, Rostislav, Negrini, Massimo, Slaby, Ondrej
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2015
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770730/
https://ncbi.nlm.nih.gov/pubmed/26497852
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