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Stepwise isotope editing of [FeFe]-hydrogenases exposes cofactor dynamics

The six-iron cofactor of [FeFe]-hydrogenases (H-cluster) is the most efficient H(2)-forming catalyst in nature. It comprises a diiron active site with three carbon monoxide (CO) and two cyanide (CN(−)) ligands in the active oxidized state (H(ox)) and one additional CO ligand in the inhibited state (...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Senger, Moritz, Mebs, Stefan, Duan, Jifu, Wittkamp, Florian, Apfel, Ulf-Peter, Heberle, Joachim, Haumann, Michael, Stripp, Sven Timo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968730/
https://ncbi.nlm.nih.gov/pubmed/27432985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1606178113
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